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PAF is an active compound in the body that is related to a variety of immunological reactions. However, it requires a steady dose of essential nutrients, which must come from food or supplements, in order to function at its best. You can find flaxseed oil in oil form, in capsules, or even in enriched food products. Flaxseed interacts with 583 drugs . View abstract. It may take 1 to 3 days before this medication starts working. Dietary phytoestrogens and lung cancer risk. National Center for Complementary and Integrative Health. View abstract. Haggans CJ, Hutchins AM, Olson BA, et al. Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways. Flax may also be used for purposes not listed in this product guide. Alpha-linolenic acid in the treatment of rheumatoid arthritis. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. Accessed Sept. 27, 2017. Cunnane SC, Ganguli S, Menard C, et al. Obes Facts 2022. Walnuts - bone loss, joint pain. The evidence is mixed as to whether flaxseed or flaxseed oil has any effect on the prostate or the risk of prostate cancer. The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency. include protected health information. Stop using flax and call your healthcare provider at once if you have: bloating, gas, stomach ache, constipation, diarrhea, and nausea. Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: A randomized trial. Flaxseed reduces some risk factors of cardiovascular disease. Hedelin M, Lof M, Olsson M, et al. Thompson LU, Chen JM, Li T, et al. Khandouzi N, Zahedmehr A, Mohammadzadeh A, Sanati HR, Nasrollahzadeh J. The effect of flaxseed supplementation on body weight and ody composition: a systematic review and meta-analysis of 45 randomized placebo-controlled trials. Flaxseed oil contains a-linolenic acid (ALA), which the body can break down into an omega-3 fatty acid. A total of 12 drugs are known to interact with green tea. Not all possible interactions are listed in this product guide. Vitamin Keven in foods such as kale, lettuce, broccoli, and chickpeascan counteract a blood thinner's benefits. Plasma enterolignan concentrations and colorectal cancer risk in a nested case-control study. Ibrgger S, Kristensen M, Mikkelsen MS, Astrup A. Flaxseed dietary fiber supplements for suppression of appetite and food intake. View abstract. Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy. Some people also take flaxseed to treat inflammatory diseases. Rodriguez-Leyva D, Rodriguez-Portelles A, Weighell W, Guzman R, Maddaford TG, Pierce GN. View abstract. Sometimes flax seed will interfere with the absorption of other medications. View abstract. Some medications that may interact with flaxseed oil negatively include: You should consult your doctor before using flaxseed oil if you have: Pregnant and nursing women should avoid the use of flaxseed oil. Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Written by Cerner Multum. Salmon, wild - bone loss, joint pain. Flaxseed oil doesn't have these phytoestrogens. Chen J, Power KA, Mann J, et al. Shim YY, et al. Coulman KD, Liu Z, Michaelides J, et al. Cabbage - Sulconazole. Moderate to vigorous physical activity, particularly aerobic exercise, has been shown to be associated with lower risk of bone fractures in women being treated with aromatase inhibitors. Additionally, the fat in flaxseed oil may not give your body what it needs if you have prostate cancer. Black Seed Oil and Diabetes: What's Known, What's Not, Harvard T.H. Flax seeds are considered to help with constipation. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. View abstract. Sairanen U, Piirainen L, Nevala R, Korpela R. Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. A deficiency of vitamin B12 can cause permanent neurological and nerve damage as well as mood changes and decreased energy. Explore (NY) 2021. However, whether flaxseed oil benefits your health is still under debate, according to the National Center for Complementary and Integrative Health (NCCIH). Effects of flaxseed and flaxseed oil supplement on serum levels of inflammatory markers, metabolic parameters and severity of disease in patients with ulcerative colitis. Your body is an amazing physiological machine. Omega 3 dietary sources include flax seeds, chia seeds, walnuts, and fish. Here are the seven side-effects of flaxseeds: 1. Haggans CJ, Travelli EJ, Thomas W, et al. You need to be careful in using these supplements if you have diabetes or any other condition that affects your blood sugar levels. Saarinen NM, Power K, Chen J, Thompson LU. Adlercreutz H, Fotsis T, Bannwart C, et al. Wong H, Chahal N, Manlhiot C, Niedra E, McCrindle BW. Getting omega-3 into your body requires eating it in your diet or consuming it as a supplement, as your body does not produce it on its own. Taylor, C. G., Noto, A. D., Stringer, D. M., Froese, S., and Malcolmson, L. Dietary milled flaxseed and flaxseed oil improve N-3 fatty acid status and do not affect glycemic control in individuals with well-controlled type 2 diabetes. Am J Clin Nutr 1999;69:549-55. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. View abstract. Herb-Drug Interactions Milk thistle is an inhibitor . However, if you're taking prescription medication, talk to your pharmacist or primary care provider about potential flaxseed oil drug interactions first. Pan A, Sun J, Chen Y, et al. Circulating enterolactone and risk of endometrial cancer. View abstract. Hailshadow/Getty Images. View abstract. DOI: What are omega-3 fatty acids from fish oil? View abstract. View abstract. Taking flaxseed by mouth may help reduce. Rich in omega-3 fatty acids, flaxseed oil is gaining ground as a functional food with many potential health benefits. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. Flax seeds are very beneficial for health because they contain a good amount of omega-3 fatty acids that cuts down the risk of heart diseases by controlling cholesterol. Oncology Nutrition advises that you should discuss the use of flax seeds with your doctor and avoid the use of flaxseed oil altogether because it provides no benefit to those with prostate cancer. View abstract. Goyal A, et al. Flaxseed oil may also lower insulin and improve antioxidant activity in people with Type 2 diabetes, according to a July 2019 randomized, double-blind, placebo-controlled study published in Phytotherapy Research. Learn about the medical uses, claims, and side effects of flaxseed. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. Flax is the seed of a plant called Linum usitatissimum, and is also known as Flax Seed, Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Flax, Echter Lein, Flachssamen, Flax Hull, Flax Lignans, Gemeiner Flachs, Graine de Lin, Kattan, Keten, Leinsamen, Lignans, Lin, Olagineux, Lin Textile, Linaza, Lini Semen, Linho, Lino, Linseed, Lint Bells, An open-label study on the effect of flax seed powder (Linum usitatissimum) supplementation in the management of diabetes mellitus. Flaxseed and flaxseed oil. The phase IV clinical study analyzes what interactions people who take Flaxseed and Metformin have. View abstract. 2013 Apr;17(2):275-81. Cancer Epidemiol Biomarkers Prev 2006;15:1132-6. Raspberries - joint pain. Finnegan YE, Minihane AM, Leigh-Firbank EC, et al. 2016 Jun;35(3):615-25. Am J Clin Nutr 2004;79:318-25.. View abstract. Atherosclerosis 1997;132:69-76. View abstract. Please contact your doctor or pharmacist. Urology 2004;63:900-4.. View abstract. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. J Natl Cancer Inst 1993;85:1571-9. Read More Created for people with ongoing healthcare needs but benefits everyone. But it can interfere with the absorption of some medications and supplements.Take oral agents one hour before -- or two hours after -- flaxseed to prevent decreased absorption. Pan A, Demark-Wahnefried W, Ye X, et al. Flaxseed oil, the most commonly used high risk supplement that contains phosphorus, was taken by 16 percent of patients with normal or mildly reduced kidney function. Flaxseed oil is generally cold pressed. . Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice. Would you believe hundred grams of flaxseeds contain 813 mg of potassium. These types of drugs, herbs and supplements reduce blood clotting. Eating flaxseeds can have gastrointestinal side effects and can significantly increase the number of bowel movements you have in a day. Touillaud MS, Thiebaut AC, Fournier A, et al. Can J Physiol Pharmacol. A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk. 2020:1-9. The omega-3 fatty acids in flaxseed meal by interact negatively with blood-thinning medications. Flax is often sold as an herbal supplement. Use caution when adding flaxseed oil to your diet or using it as a supplement. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. View abstract. Asia Pac J Clin Nutr. View abstract. View abstract. A prospective study of dietary fat and risk of prostate cancer. The use of flax seeds may increase your chances of bleeding. Yang C, Xia H, Wan M, et al. Accessed Sept. 27, 2017. Most of the animal studies have focused on breast cancer. Flaxseed oil might lower blood pressure. Flaxseed is often mixed with foods and used in baked goods, such as muffins, breads, and snack bars. Adlercreutz H, Heikkinen R, Woods M, et al. Certain herbal supplements, such as St. John's wort, may decrease blood levels of some statin drugs, and when taken with atorvastatin, may . Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Diclofenac (Voltaren, Cataflam, Voltaren-XR, Cambia) is a nonsteroidal anti-inflammatory medication prescribed to treat inflammation and pain caused by conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and menstrual cramps. 2013;23(6):446-7. Possible drug interactions: Can reduce blood levels and effectiveness of many drugs, including birth control pills, cholesterol-lowering statins and some anti-HIV drugs. Omega-3 fats are best known for improving heart health, but your body uses the essential fat to perform many vital functions, including the formation of cell membranes and the creation of hormones that control blood clotting, blood vessel function and inflammation. View abstract. Flaxseed is packed with beneficial nutrients, omega-3 fatty acids, and fiber. February 23, 2023. Most of the health benefits associated with omega-3 fatty acids from improving heart health to reducing inflammation are due to EPA and DHA, which come from fish and fish oil. This content does not have an Arabic version. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. J Steroid Biochem Mol Biol 1994;50:205-12.. View abstract. Oral drugs. Demark-Wahnefried W, Price DT, Polascik TJ, et al. 2021;75(1):99-111. Flaxseed (Linum usitatissimum) and flaxseed oil, which comes from flaxseed, are rich sources of the essential fatty acid alpha-linolenic acid a heart-healthy omega-3 fatty acid. View abstract. information highlighted below and resubmit the form. Rhee Y, Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Just 500 Extra Steps a Day Can Lower Heart Disease Risk in Seniors, Study Suggests . View abstract. View abstract. View abstract. 2005-2023 Healthline Media a Red Ventures Company. It isn't always safe to take flaxseed oil with other medicines. National Institutes of Health: Office of Dietary Supplements: "Omega-3 Fatty Acids", Journal of Food Science and Technology: "Flax and Flaxseed Oil: An Ancient Medicine & Modern Functional Food", Harvard T.H. Learn how we can help 3.9k views Reviewed >2 years ago Thank Dr. John Munshower and 4 doctors agree 1 thank Brouwer IA, Katan MB, Zock PL. Call your doctor if the condition you are treating with flax does not improve, or if it gets worse while using this product. Common interactions include fatigue among females and drug ineffective among males. These medications may cause some risk when taken together. You may be eager to find a supplement to boost the omega-3 fatty acids in your body. Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity. Int J Cancer 2005;116:793-8. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in postmenopausal women. Wang Wuyu suddenly woke up and sat up, his stomach made a loud noise like a drum beating. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, There are many studies currently under way, flax seeds may increase your chances of bleeding, Interactions with medications and health conditions, nccih.nih.gov/health/flaxseed/ataglance.htm, mayoclinic.org/drugs-supplements/flaxseed-and-flaxseed-oil/background/hrb-20059416, oncologynutrition.org/erfc/healthy-nutrition-now/flaxseed-prostate-cancer-risk/, pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000959, mayoclinic.org/what-are-omega-3-fatty-acids-from-fish-oil/art-20232583, health.harvard.edu/heart-health/why-not-flaxseed-oil, 6 Benefits of Flaxseed Oil Plus How to Use It. View abstract. Flaxseed oil is a supplement that can boost your intake of omega-3 fatty acids. Fish oil may be a better and safer choice. You should stop consuming these seeds, if you notice any itching, swelling, redness, or hives. This will help prevent any negative reactions that might arise. Am J Clin Nutr 1997;66:591-8. Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. Here are 9 teas that help treat stomach problems. Taking flaxseed by mouth seems to help reduce, Breast pain (mastalgia). those that regulate blood sugar, including. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. J Am Coll Nutr 1993;12:501-4. Yari Z, Rahimlou M, Eslamparast T, Ebrahimi-Daryani N, Poustchi H, Hekmatdoost A. Flaxseed supplementation in non-alcoholic fatty liver disease: a pilot randomized, open labeled, controlled study. Obstet Gynecol 2002;100:495-504.. View abstract. It is not intended to replace professional veterinary advice or care. Br J Nutr. View abstract. Flaxseed oil may be rich in omega-3 fatty acids, but it may not be the right type. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: Flax is considered likely unsafe to use during pregnancy. Lifestyle counseling and supplementation with flaxseed or walnuts influence the management of metabolic syndrome. View abstract. Jenkins DJ, Kendall CW, Vidgen E, et al. List Flaxseed side effects by likelihood and severity. View abstract. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. View abstract. Even though the nutritional profile of flaxseeds may be useful for improving the function of the Thyroid, it is important to consider that there is also one particular concerning the fact that need to be taken into account. J Med Food. Alonso L, Marcos ML, Blanco JG, et al. May cause allergic reactions. Cancer Causes Control 2008;19:259-72. Ursoniu S, Sahebkar A, Andrica F, Serban C, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration Group. However, it may cause undesirable side effects if you have a preexisting medical condition, use certain medications, or take the wrong dosage. Furthermore, some thyroid medications can interfere with vitamin D absorption or metabolism, resulting in low vitamin D levels. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. February 24, 2023. Certain antibioticsspecifically quinolone antibiotics (like Cipro) and tetracycline antibiotics (like Achromycin and Sumycin)interact with zinc in the gastrointestinal tract and don't allow the. Lampe JW, Martini MC, Kurzer MS, et al. Medications taken by mouth (Oral drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider. Vomiting and nausea could also be an indicator of an allergy. Some medications that may interact with flaxseed oil negatively include: those that alter your blood flow and bleeding, including: aspirin blood thinners, like warfarin (Coumadin) and. Breast Cancer Res Treat 2000;64:49. Flaxseed oil drug interactions may also improve the effectiveness of some medications, notes Mount Sinai, including nonsteroidal anti-inflammatory drugs and prescription medications that lower blood cholesterol. Cockerell KM, Watkins AS, Reeves LB, et al. Flax is the seed of a plant called Linum usitatissimum, and is also known as Flax Seed, Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Flax, Echter Lein, Flachssamen, Flax Hull, Flax Lignans, Gemeiner Flachs, Graine de Lin, Kattan, Keten, Leinsamen, Lignans, Lin, Olagineux, Lin Textile, Linaza, Lini Semen, Linho, Lino, Linseed, Lint Bells, Linum, Malsag, Phytoestrogen, Ta Ma, Tisii, Winterlien, and other names. We comply with the HONcode standard for trustworthy health information. 2019;46:36-43. Though tiny, they are rich in the omega-3 fatty acid ALA, lignans and fiber, all of which have been shown to have many potential health . Zhang W, Wang X, Liu Y, et al. J Steroid Biochem Mol Biol 1992;41:615-9.. View abstract. 2019:1-8. Store at room temperature away from moisture and heat. Available for Android and iOS devices. Accessed Sept. 27, 2017. Ultimately, if flaxseed is to blame, an upped dosage of levothyroxine medication is probably needed going further. Medications are the primary treatment for hypertension; however, adherence to drug regimens is low (~50 %). Appl Physiol Nutr Metab 2009;34:89-98. Beta . This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Other drugs may interact with flax, including prescription and over-the-counter medicines, vitamins, and herbal products. Its important to be cautious when using flaxseed oil, as there are several risks and side effects. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. Natural Medicines. The Mayo Clinic warns that using flaxseed oil with this blood thinner, or any other anticoagulant, may increase your risk of bleeding. Flaxseeds are a good source of. View abstract. Similar to the hormone estrogen, phytoestrogens might have anti-cancer properties. 2013 Dec;62(6):1081-9. 1 Severe Side Effects Summary: Drug interactions are reported among people who take Flaxseed and Metformin. Excess sodium disturbs the water. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Information from this source is evidence-based and objective, and without commercial influence. View abstract. View abstract. What Are the Benefits of Flaxseed Oil Pills? Clin Cancer Res 2004;10:7703-11. Bloedon LT, Balikai S, Chittams J, et al. Leitzmann MF, Stampfer MJ, Michaud DS, et al. de Deckere EAM, Korver O, Verschuren PM, Katan MB. There is a chance you may have an allergy to flax seeds and flaxseed oil. Cornish SM, Chilibeck PD, Paus-Jennsen L, et al. Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh Y. All rights reserved. Do not use more of this product than is recommended on the label. Flaxseed oil doesnt contain fiber like flax seeds, however. J Am Coll Nutr 2008;27:65-74. View abstract. Koizumi Y, Arai H, Nagase H, Kano S, Tachizawa N, Sagawa T, Yamaguchi M, Ohta K. [Case report: anaphylaxis caused by linseed included in baked bread]. Flaxseed and prostate cancer risk. those that alter your blood flow and bleeding, including: some nonsteroidal anti-inflammatory drugs, like ibuprofen and naproxen. View abstract. This information may not fit your specific health circumstances. Colli MC, Bracht A, Soares AA, et al. What medications does flaxseed interfere with? To help you remember, take it at the same time(s) each day. Br J Cancer 2008;98:636-40. Clark WF, Parbtani A, Huff MW, et al. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. are using cholesterol-lowering drugs. Taking flaxseed along with diabetes medications might cause blood sugar to drop too low. WebMD does not provide medical advice, diagnosis or treatment. Pan A, Yu D, Demark-Wahnefried W, et al. View abstract. Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women. Flaxseed might lower blood pressure. Rose DP. Hemodial Int. View abstract. Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women. If you take insulin or other medication for diabetes, consult your physician before consuming flaxseed meal. Common interactions include back pain among females and flushing among males. does flaxseed interfere with blood pressure medication Master, I m hungry. The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women. This is not a complete list of side effects and others may occur. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Effects of Vitex agnus and flaxseed on cyclic mastalgia: a randomized controlled trial. Flaxseed is considered to be a goitrogen. J Res Med Sci. Consult with a licensed healthcare professional before using any herbal/health supplement. Accessed Sept. 27, 2017. Eur J Clin Nutr 2007;61:1423-8. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 1995;49(3):169-178. Soltanian N, Janghorbani M. Effect of flaxseed or psyllium vs. placebo on management of constipation, weight, glycemia, and lipids: A randomized trial in constipated patients with type 2 diabetes. Flaxseed oil also might decrease blood clotting. View abstract. View abstract. Khalesi S, Irwin C, Schubert M. Flaxseed consumption may reduce blood pressure: a systematic review and meta-analysis of controlled trials. Consult your healthcare professional (e.g., doctor or pharmacist). Eating a flaxseed muffin daily for 3 months or taking flaxseed powder by mouth daily for 2 months seems to reduce breast pain that occurs at the start of the, Obesity. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Zeleniuch-Jacquotte A, Lundin E, Micheli A, et al. https://nccih.nih.gov/research/results/spotlight/062308.htm. Fish, walnuts, chia seeds and flaxseed oil are excellent sources of omega-3 fats. Menopause 2006;13:631-42. This article reviews the benefits, safety, and side, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Hashempur MH, Homayouni K, Ashraf A, Salehi A, Taghizadeh M, Heydari M. Effect of Linum usitatissimum L. (linseed) oil on mild and moderate carpal tunnel syndrome: a randomized, double-blind, placebo-controlled clinical trial. Nutr Cancer 1990;13:1-8.. View abstract. Pharmacol Res. Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN. Chen J, Power KA, Mann J, et al. View abstract. Flaxseed is high in soluble fiber and in lignans, which contain phytoestrogens. Flaxseed - More Interactions. 2016 Feb;25:90-5. Dietary flavonoid intake and breast cancer risk among women on Long Island. Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts. Advertising revenue supports our not-for-profit mission. Morshedzadeh N, Shahrokh S, Aghdaei HA, et al. Flaxseed oil contains ALA, which your body primarily uses as a source of energy, according to Harvard T.H. View abstract. Flaxseed has most often been used by adults in doses of 20-30 grams by mouth daily. Though your body contains enzymes that convert ALA from flaxseed oil into EPA and DHA, your body only converts 10 to 15 percent of the ALA, says Harvard Health Publishing. The effectiveness of your oral contraceptives or hormonal therapy may also be affected by flaxseed meal consumption. If you need surgery, dental work, or a medical procedure, stop taking flax at least 2 weeks ahead of time. Natural Medicines. According to WebMD, "Research suggests that plant omega-3s help the cardiovascular system through several different mechanisms, including anti-inflammatory action and normalizing the heartbeat. 2015 Apr;145(4):758-65. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Morshedzadeh N, Rahimlou M, Shahrokh S, Karimi S, Mirmiran P, Zali MR. Grapefruit and their products contain a natural chemical that interfere with the break down of certain medications, such as simvastatin and atorvastatin.